At a minimum, you’ll want to perform regular backups of your vCenter, Update Manager, and System databases. You don’t have to be a DBA to perform simple backups. You don’t need to know T-SQL or database programming to perform these steps. There’s an easy wizard that walks you through a standard Windows Next-Next-Finish set up.
There are a couple things to note in the walkthrough below. We’re using SQL Server 2008 Enterprise Edition 64-bit on a 64-bit Windows Server 2008 SP2 Enterprise Edition. The SQL server is also a virtual machine in a vSphere 4.1 environment.