I was performing my first upgrade past 2.2(3) this weekend (upgrading to 2.2(5)) and I came across a small change that took some googling to figure out. Eventually, I found the resolution in the Release Notes. If you’re performing a manual upgrade to 2.2(4b) or later, you have to clear the Startup Version of the Default Infrastructure Pack. This action is the result of bug fix CSCus73964 and can be found in the Behavior Changes section of the 2.2 Release Notes.
The error occurred when trying to Activate the firmware of the IO Modules. It states, “Failed start activation. Manual upgrade/activation is disallowed because the Default Infrastructure Policy ‘Startup Version’ is set. Retry the operation after changing the version to ‘Not Set.'”
The UCSM GUI option to clear the startup version on the Auto Install tab was grayed out so I couldn’t clear it from there. The Firmware Management CLI Guide offered the CLI solution to clearing it, though, and it worked fine.